Pathways of Apoptosis in Lymphocyte Development, Homeostasis, and Disease
نویسندگان
چکیده
Apoptosis plays a critical role in lymphocyte development and homeostasis. Enhanced lymphocyte apoptosis can cause immunodeficiency through cell loss. Conversely, inhibition of apoptosis can lead to the development of autoimmunity or lymphoma. Two major pathways contribute to the regulation of lymphocyte cell death, death-by-neglect and death-by-instruction.
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ورودعنوان ژورنال:
- Cell
دوره 109 شماره
صفحات -
تاریخ انتشار 2002